Boyd Haley, PhD

Dr. Haley received his BS in Chemistry/Physics from Franklin College in 1963. After a tour in the U.S. Army (Medic MOS) he completed his M.S. in Chemistry at the University of Idaho (1966) and his Ph.D. in Chemistry/Biochemistry at Washington State University (1971). He was an NIH Postdoctoral Scholar in the Department of Physiology, Yale University Medical School from 1971 to 1974. His first academic appointment was at the University of Wyoming in 1974 where he was promoted to full professor in 1983. In 1985 he was appointed as the first scientist hired in the Markey Cancer Center at the University of Kentucky with academic appointments as professor in the College of Pharmacy and in the Department of Biochemistry of the University of Kentucky Medical Center. In 1996 he was named Professor and Chair of the Department of Chemistry. He is also co-founder and scientific advisor of Affinity Labeling Technologies, Inc., a biotech company that synthesizes and markets to major research institutes nucleotide photoaffinity analogs for biomedical research. He is also developed a diagnostic test (published in the Proc. National Academy of Science, 1992) for Alzheimer’s disease that is being commercially developed by SynXpharma with support from J&J..

Since 1987 Dr. Haley has emphasized studies on Alzheimer’s disease in his laboratory. His research in the biochemical aberrancies in Alzheimer’s disease also lead to his identifying mercury toxicity as a major exacerbating factor, perhaps even a causal factor. He was one of the first to propose that the organic-mercury preservative (thimerosal) in infant vaccines was the most likely toxic agent involved in autism related disorders. He has followed this up with research that demonstrates that several additional factors (Al 3+, certain antibiotics), including testosterone, increase the toxicity of thimerosal. Further, in collaboration with others it has been shown using birth-hair analysis that autistics represent a subset of the population that do not excrete mercury effectively. In the past few years Dr. Haley has testified before numerous government agencies on the effects of mercury toxicity from dental amalgams and vaccines. This list includes two times before the Congressional Committee on Government Reform, the Pentagon to Surgeon Generals, the Institute of Medicine of the National Academy of Sciences and legislative committees of the states of Maine and New Hampshire . In the latter situation, both states enacted legislation requiring dentists to inform patients of the 50% mercury in dental amalgam fillings and the concern of many that emission of mercury from these amalgams affects personal health. He is also a member of the Autism Think Tank of the Autism Association. Dr. Haley has also been invited and presented his lectures on this subject at international conferences in England , Canada , Australia , Sweden , France , Germany , New Zealand , Mexico , Italy and Denmark .



BOYD E. HALEY , Ph.D. Born 22-09-40 Greensburg , Indiana


EDUCATION:

Franklin College 1963 B.A./Chemistry-Physics
University of Idaho 1967 M.S./Organic Chemistry
Washington State University 1971 Ph.D./Chemistry-Biochemistry
Yale University Medical Center 1971-74 Postdoctoral Fellow

RESEARCH AND PROFESSIONAL EXPERIENCE:

1963-1964 Research Scholar, Food and Drug Administration.
1964-1966 U.S. Army Medic
1966-1967 Graduate Student, University of Idaho
1967-1971 Graduate Student, Washington State University
1971-1974 Postdoctoral Scholar, Yale University
1974-1979 Assistant Professor, Department of Biochemistry, University of Wyoming, Laramie, WY
1979-1981 Associate Professor, Department of Biochemistry, University of Wyoming, Laramie, WY
1981-1985 Professor, Department of Biochemistry, University of Wyoming, Laramie, WY
1985-1997 Professor of Medicinal Chemistry, College of Pharmacy, University of Kentucky, with joint appointments in Biochemistry & Chemistry
1994-present Scientific Advisor and Founder of Affinity Labeling Technologies in ASTeCC Chairman & Professor, Department of Chemistry
2005-present Professor, Department of Chemistry
2006-present Scientific Advisor for AL T Bioscience (reformed from Affinity Labeling Technologies)



PROFESSIONAL ORGANIZATIONS, SOCIETIES, HONORS AND RESPONSIBILITIES

1959 President's Scholarship, Franklin College , Indiana
1962 Chi Beta Phi, Franklin College
1962 James M. Sprague Award - $400 award to outstanding undergraduate junior majoring in science.
1963 Kennedy Scholar, Food and Drug Administration, Washington , D.C.
1970 Sigma Xi
1975 Dreyfus Foundation Visiting Researcher, Enzyme Institute University of Wisconsin
1977 American Society of Biological Chemists
1981 Biophysical Society
1981 Served on NIH Physiological Chemistry Study Section
1981 Research was presented as a "highlight" in NIH report on "Cellular and Molecular Basis of Disease Program"
1984 "TOP" Professor Award, University of Wyoming
1982 Served on NIH Physiological Chemistry Study Section
1983 Served on NIH Physiological Chemistry Study Section
1985 Permanent member NIH Biomedical Sciences, Study Section
1991 Honorary Doctorate in Arts & Sciences, Franklin College
1992 Society for Neuroscience
Elected Fellow in International Academy of Oral and Medical Toxicology (IAOMT)
1996-2005 Board of Trustees, Franklin College
2005 Awarded the Humanatarion Award by the International Academy of Oral and Medical Toxicology (IAOMT)
2006 Awarded the level of Master of IAOMT

GRANT SUPPORT

1975 - 1978 National Institutes of Health, "Application of Photoaffinity Nucleotide Analogs", $82,000, Prinicipal Investigator
1975 Research Coordination Committee, University of Wyoming $1,800
1978 - 1981 National Institutes of Health, "Application of Photoaffinity Nucleotide Analogs", $183,696, Prinicipal Investigator 1978 - 1981 Eleanor Roosevelt Cancer Institute Grant, $11,400 1979 - 1983 PHS Research Career Development Award, $185,000 1981 - 1986 National Institutes of Health, "Application of Photoaffinity Nucleotide Analogs", $434,000, Prinicipal Investigator 1982 ASBC Travel Award to attend 12th IVB Congress, Perth , Australia
1983 - 1984 National Science Foundation, "Melatonin Photoaffinity Probe", $84,000, Co-Principal Investigator
1983 - 1985 National Institutes of Health, "Epididymal Sperm Nucleotide Binding proteins", $190,000, Co-Principal Investigator 1985 - 1988 U.S. Army Mycotoxin Photoprobes, $390,000, Co-Principal Investigator
1986 - 1989 NIH, "Forskolin Photoaffinity Probes", $170,000, Co-Principal Investigator
1986 - 1991 NIH, "Application of Photoaffinity Nucleotide Analogs" $781,661, Principal Investigator
1989 - 1994 NIH, "Nucleotide-Tubulin Interactions in Alzheimer's Disease", $405,259, Co-Prinicipal Investigator
1990 - 1996 Lexington Clinic Foundation For Medical Education and Research, "Inhibition of Neoplastic Cell Proliferation Through Utilization of Photoactive DNA & RNA Synthesis, $100,000, P.I.
1990 - 1993 Eli Lilly, "Development of a Diagnostic Test for Alzheimer's Disease, $378,000, P.I.
1995 - 1997 Wallace Research Foundation, “Development of Diagnostic Tests Using Nucleotide Photoaffinity Probes”. $109,000 for two years.
1997-1998 Wallace Research Foundation, “Development of Diagnostic Tests Using Nucleotide Photoaffinity Probes”. $74,344. 1997-2000 NIH, “Application of Photoaffinity Nucleotide Analogs”, $378,081, P.I.
1997-1998 Isostent, Inc. “Photoattachment of 32P to angioplastic ballon cathers” $52,000.
Wallace Research Foundation “Studies on the Neurotoxicity of Mercury” $150,000
Wallace Resarch Foundation “Studies on Mercury Neurotoxic Effects at the CellularLevel” $116,520
Wallace Research Foundation “Vaccine & Thimerosal Toxicity Studies” $112,720
Wallace Research Foundation “Synergistic Neurotoxicity of Thimerosal & other compounds.” $78,720.
2003-2003 Autism Research Institute “Neurotoxicity of Thimerosal” $30,000
Wallace Research Foundation “Vaccine thimerosal exposure and its releationship to Autism” $75,704
Wallace Research Foundation “Synthesis of Biologically Based Mercury Chelators which Cross Cell Membrane and the Blood Brain Barrier” $109,558 Starts December 2004
2005 Gift for Mercury research from the HB Wyatt estate, $482,000.

TEACHING EXPERIENCE

Introductory Comparative Biochemistry
General Biochemistry
Problems and Topics in Biochemistry
Mercury Toxicity: Chemistry and Biochemistry Involved
Advanced Problems and Topics in Biochemistry
Nucleic Acids and Protein Biosynthesis

Nucleotides in Regulation of Biological Phenomena
Bioenergetics
Medicinal Chemistry

Natural Products and Bio-organics
Graduate level Biochemistry, Protein Chemistry, Biological Chemistry

Mercury, Science and Politics

Chemistry for Citizens

Chemistry 108 organic and biochemistry for non-majors

INVITED LECTURES:

1975 - Sloan Kettering Memorial Cancer Institute, New York
thru Colorado State University (3)
1979 Albert Einstein University, New York
Hoffman-LaRoche Research Institute, Nutley, New Jersey
University of Colorado Medical School Denver (3)
University of Colorado, Boulder (2)
Yale University Medical School (2)
The Salk Institute, San Diego
University of California, Davis
Stanford University Medical School
University of California, San Diego
University of Washington, Seattle
Washington State University
Kansas State University
1979 Symposium Speaker, ASBC Meeting, Dallas, Texas
1979 Symposium Speaker, New York Academy of Sciences Meeting, New York Department of Molecular Biology, National Jewish Hospital, Denver
University of California, Riverside
Workshop Speaker, ICN-UCLA Conference on Adenylyl Cyclase
1982 Symposium Speaker, 1982 FASEB Meeting, New Orleans
1982 Guest Lecturer and Scientist, German Cancer Research Center,
Institute of Cell and Tumor Biology, Heidelberg, West Germany,
May
1982 Centre National De La Recherche Scientifique, Laboratoire
D'Enzymologie, Gif Sur Yvette, France, June
1982 Workshop Speaker, ASBC Meeting in New Orleans (Photoprobe
utilization, sponsored by Schwarz-Mann)
1982 Symposium Speaker, Society for the Study of Reproduction, Madison
Wisconsin, August
1982 Department of Biochemistry, University of Wisconsin, November
1982 Department of Chemistry, New Mexico State University, November
1982 Department of Chemistry, University of Colorado, December
1983 Institute of Infectious Diseases, U.S. Army Medical Research
Institute, Ft. Detrick, Michigan, January
1983 Department of Biochemistry and Biophysics, Oregon State University
1983 Department of Biochemistry, Texas Health Science Center, San Antonio, TX
1983 Department of Biochemistry, University of Mississippi Medical Center
1984 Department of Biochemistry, University of Kentucky, Lexington, KY
1985 Department of Physiology and Biophysics, Northwestern University Medical School , Chicago , Illinois
1985 Department of Chemistry, University of Southern California, Los
Angeles, California
1985 Department of Physiology, University of Illionis at Chicago,
Chicago, Illinois
1985 Department of Biochemistry, Ohio State University, Columbus, Ohio
1985 Department of Physiology, Yale University Medical School, New Haven, Connecticut
1986 Department of Biochemistry, Case Western University, School of Medicine, Cleveland, Ohio
1986 Department of Biochemistry, Indiana University, School of Medicine, Indianapolis, Indiana
1986 Department of Biochemistry, Washington University, School of Medicine, St. Louis, Missouri
1987 Division Fermentation Products Research Division, Eli Lilly
Research Laboratories, Indianapolis, Indiana
1987 Department of Chemistry, University of South Florida, Tampa, Florida
1987 Department of Molecular Biology and Biochemistry, University of
Wyoming, Laramie, Wyoming
1988 Worcester Foundation, Shrewsbury, Massachusetts
1988 Department of Biochemistry, University of Colorado, Denver, Colorado
1988 Department of Biochemistry, University of Delaware, Newark, Delaware
1989 University of California at San Diego
1989 University of California at Los Angeles
1989 Texas College of Osteopathic Medicine, Fort Worth, Texas
1990 Wright State University, Dayton, Ohio
1990 Athena Neurosciences, S. San Francisco, California
1990 Eli Lilly & Co., Indianapolis, Indiana
1990 Connaught Laboratories, Toronto, Canada
1990 University of East Carolina Medical School, Greenville, North Carolina
1990 Hoffman-LaRoche Research Center, Nutley, New Jersey
1991 Eli Lilly & Co., Indianapolis, Indiana
1991 City University of New York , New York , New York
1991 University of Cincinnati , Cincinnati , Ohio
1991 University of Colorado , Boulder , Colorado
1991 University of Missouri at Kansas , Kansas City , Missouri
1992 Williams College at Williamsburg , Massachusetts
1992 Centre College at Danville , Kentucky
1992 University of Colorado , Boulder , Colorado
1992 Eli Lilly & Co. , Indianapolis , Indiana
1992 Merck Laboratories, West Point , Pennsylvania
1993 NIH Rocky Mountain Laboratory, Hamilton , MT
1993 Intern. Acad. Oral & Medical Toxicology, Chicago , IL
1993 Univ. Tenn. at Memphis , Memphis , TN
1993 Penn State University , College Station , PN
1993 University California , Riverside , Riverside , CA
1993 Mayo Clinic, Jacksonville , FL
1993 Washington University , St. Louis , MO
1993 University of Arkansas , Little Rock , AR
1994 European Academy of Science, Otzenhausen , Germany
1994 Intern. Acad. Oral & Medical Toxicology, London , England .
1994 Great Lakes College for Advancement of Medicine, Cincinnati , OH
1995 American College for the Advancement of Medicine, Colorado Springs, CO.
1995 Pfizer Pharmaceuticals, Groton , CN
1995 Ohio State University , Dept,. Chemistry, Columbus , OH
1996 Intern. Acad. Oral & Medical Toxicology, Tuscon , AZ
1996 University of Wyoming , Laramie WY
1996 American College for the Advancement of Medicine, Colorado Springs, CO.
1997 American Academy Biological Dentistry, Carmel , CA March 7-9.
1997 International Academy of Oral and Medical Toxicology, Louisville , KY March 14-16
1997 Washington State University , Dept. of Chemistry and Biophysics, Pullman , WA , March 27-30.
1997 American Society of Biochemistry and Molecular Biology, Symposium talk, August 24-28.
1997 Canadian Academy Oral and Medical Toxicology, Toronto , Canada . September 19-21.
1997 Capital University of Integrative Medicine, Washington , DC , October 16-18
1997 American Academy Environmental Medicine, San Diego , CA , October 24-26.
1997 University of Missouri at Kansas City , Dept. Biology & Biophysics, November 20-22.
1997 through 2002: I have given invited symposium talks on mercury toxicity at the rate of about 6-8 per year. These talks are throughout the USA with several being given in foreign countries including England , Canada , France , Germany , New Zealand , Belgium and Australia .
2001 Invited speaker, Institute of Medicine on thimerosal and autism.
2002 House Government Reform Committee, November 14, http://www.house.gov/reform/haley.02.11.14.htm



26 Talks given in 2003.

Wayne State University , Dept. of Chemistry Jan 17 th Dept. Pediatrics, University of Kentucky , Grand Rounds Speaker Jan 23 rd.
Autism Society of Central Kentucky , Century Methodist Church Jan. 27
Arizona State University , Department of Bioengineering Feb 23-25
Mealy Vaccine Conference, Boston MA , March 6-7
Autism One Political Rally with Congressman Dan Burton, Washington , DC March 19.
International Academy of Oral & Medical Toxicology, Las Vegas , NV March 28 th.
Autism Society of America/OCC, Pontiac , MI March 29 th.
Zeins’s Dental Conference, Newark , NJ . April 11 th.
Greater Louisville Dental Study Group, Louisville , KY April 16 th
Speaker, UK Chemistry Dept. Awards Ceremony, April 25 th.
Autism One Conference, University of Loyala , Chicago , IL May 3-4
Expert Witness, Congressional Committee on Government Reform, Dan Burton, Washington , DC May 7-8 th
Speaker, UK Superfund Environmental Project, Paducah , KY (by Sandra Bastin) May 13
Defeat Autism Now (DAN) Conference, Philadelphia , PE 15-18 th May
Wallace Research Foundation, Phoeniz , AZ May 19-21 st
Wright State University , graduate recruitment seminar, May 23 rd
Swedish Heavy Metals Biology Research Group, June 11-15. I am a board member. Uppsalla , Sweden
Heavy Metals InstituteTask Force , Washington , DC., 19-22 June
Missouri University Research Reactor, Columbia , MO , 1-3 July
Doctors for Disaster Prepardness Conference, Phoeniz , AZ , July 12-13
Autism One Congressional Press Conference, Washington , DC July 23
Mercury Medical/Neurotoxicology Conference, NY,NY Sept. 10
American Board of Clinical Medical Toxicology (ABCMT) St. Louis , MO , Sept. 11
Italian Congress on Metal Toxicity, Teatro congressi P. d’Abano, Largo Marconi n.1-35031 Abano Terme, Italy.November 7-12. I am also chairman of one of the sessions.

25 Invited SymposiumTalks, University Invitations and other presentations given in 2004.

Attorney General’s Office, State of New York 5 January
TV Interview WBNS-TV Columbus , OH 16 January
Student ACS section, Lexington , KY 28 January
NSF Progam Evaluator, Washington , DC 4 February
NAS Institute of Medicine, 9-10 February
Dr. Ruth Koslack Talk Show, 11 February
Congres International Toxicite of the Heavy Metaux, Geneva , Switzerland 27 February
Dipartimento Di Scienze Biomolecolari Biotecnologie, University of Milan , Milan , Italy 28 February
International Academy of Oral Medicine and Toxicology, Arlington , VA , 25-27 March
Owensburo Country Club, A&S Fund Raiser, Owensburo , KY 15 April
American Academy of Environmental Medicine , St louis , Missouri , 19 April
Autism One Conference, Chicago , IL 27-30 April
Shankland Dental Conference, Columbus , OH , 24 March
American College for the Advancement of Medicine, Orlando , FL 18-20 May
TV Interview with CBS News in Washington , DC , 26 May
Autism One, Chicago Illinois , May 28-30
Congressional/IOM News Conference, Washington , DC 2 June
Tennessee Autism Association, Chattanooga , TN 4-5 June
Presentation to Congressman Patrick Kennedy and other US Congressmen, 16 June
Presentation to California Legislature on Autism 22 June
Doctors for Disaster Prepardness Conference 26-28 June
Attorney General’s Office, State of California , 9-10 August
University of Louisville , Department of Chemistry, 10 September
State of California , expert witness, Sacramento , CA 14-16 September
Tulane University Conference on Mercury Toxicity, New Orleans , LA 24 September
Washington State University , Department of Chemistry/Biochemistry 25 September
Autism Research Institute Think Tank Presenter, San Diego , CA 29 September
Defeat Autism Now Conference, San Diego , CA 30 September
International Academy of Oral Medicine and Toxicology, Nashville , TN 7-9 October
Presentation to Senator Grassley and other Congressional members on Autism, Washington , DC., 12 October
Pikeville College of Osteopathic Medicine, Pikeville , KY 22 October
TV Interview WLKY of Louisville , KY 27 October
Auburn University , Defeat Autism Now Mini-Conference, Auburn , AL 5-6 November
Geneva Center on Autism Conference, Toronto , Canada 11-12 November

Invited Talks in 2005

Autism Symposium by Autism Thoughtful House, Austin , TX 1-3 March
Interviewed by Robert Kennedy on Ring of Fire talk show 5 March
Autism Symposium by Deidre Imus Children’s Center Newark, NJ 5-6 March
Radio Liberty talk show interview by Dr. Stanly Montcrief
Presentation to Dr. Bill Raub, NIEHS on mercury toxicity 16 May
Speaker at American College of Academic Medicine, Orlando , FL
Speaker at Autism One Conference, Chicago , IL May 27-29
Speaker at United Methodist Church Regional Conference, Hampton , VA June 15
Presentation to Congressman David Weldon and others Washington , DC June 8
Speaker at Autism Rally, Washington , DC July 20
Presentation to NIHES, Environmental Factors and Neurological Disorders, Bethesday, MD August 25 th
Speaker at International Academy of Oral and Medical Toxicology, Las Vegas , NV September 9-11
Speaker at the Greater Colorado Autism Association, Boulder, CO September 30-October 2.
Presenter at the “Antecedent Biomarkers for Alzheimer’s Disease Conference” at Washington University in St. Louis , Missouri 7-8 October, 2005
Speaker at the Scottish Autism Conference in Edinburgh , Scotland on October 13 to 16, 2005 .
Speaker at the Northern Kentucky Autism Conference at N. Kentucky University on October 22, 2005 .
Speaker at the Defeat Autism Now Think Tank and Conference in Long Beach , CA on October 26-28 th, 2005 .
Invited Expert for testimony before the Tennessee Legislature on 1 November 2005 .
Invited Speaker for the Kentucky Association of Naturopathic Physicians, Louisville , KY November 5, 2005 .
Invited Speaker to the National Autism Association in Myrtle Beach , NC on Novermber 11-12, 2005.
Invited Speaker at the Louisville Rotary Club on November 17, 2005 .
Invited Speaker at the Swiss Autism Association, Zurich , Switzerland , December 1-6, 2005 .

Invited Talks 2006

Invited presenter. Dikici, E., Bhattacharyya, A. and Haley, B. Rationale for the detection and quantification of glutamine synthetase in the serum and cerebrospinal fluid as a potential diagnostic test for Alzheimer’s disease and amyotrophic lateral sclerosis. Presented at the “Antecedent Biomarkers for Alzheimer’s Disease Conference” at Washington University in St. Louis , Missouri 7-8 October, 2006
Invited speaker, Kentucky Autism Commission, Louisville , KY January 21, 2006
Invited speaker, University of Louisville , Dept Chem. Engineering January 27, 2006
Invited speaker, Health Realities Symposium, Orlando , FL February 4-5, 2006
Expert Witness, State of Connecticut , New Britain , CN February 8, 2006
Invited speaker, Autism Society of Bluegrass, Lexington , Ky February 25, 2006
Invited speaker, Great Plains Autism conference, Orlando , FL , March 4-5
Presenter, press conference in Washington , DC on autism March 8, 2006
Invited speaker, International Academy Oral and Medical Toxicology, Arlington , VA March 9-11, 2006
Invited Speaker, International College of Integrative Medicine, Chicago , IL March 22, 2006
Expert Witness, State of Connecticut , New Britain , CN March 31, 2006
Invited speaker, Kentucky Autism Association, Owensburo , KY May 15, 2006
Invited Speaker, Dental Mercury Summit , Baltimore , MD June 9, 2006
Invited speaker, Moms Against Mercury, Atlanta , GA June 28, 2006
Invited Speaker, U.S. Autism and Aspergers Association, Salt Lake , UT , August 9-11, 2006
Invited expert testimony, FDA hearing on dental amalgam, Gaithersburg , MD , September 7, 2006
Invited speaker, International Academy of Oral and Medical Toxicology, W. Palm Beach , FL , Sept. 8-10, 2006
Invited speaker, American College of Academic Medicine, Palm Springs , CA November 1-3, 2006
Invited speaker, Eastern Kentucky University , December 2006

Invited Talks 2007

University of Calgary , Calgary , Alberta Canada 19 January 2007
Invited expert, State Legislative committees of Nebraska , Iowa and Missouri , January 22, 23, 24, 25 th, 2007.
Invited speaker, Bournmouth , England . Autism is Treatable Fonference 9-10 February, 2007.
Invited speaker, Phoenix , AZ International Academy Biological Dentistry conference, 17 February 2007 .
Invited speaker, Tuscon , AZ Internation Academy of Oral and Medical Toxicology, 14-16 March 2007.
Presentation to Congressmen Moran ( Virginia ) and Weldon (FL) in Washington , DC . .22 March 2007.
Invited expert, Arkansas legislative committee, Little Rock , AK 25-26 March, 2007.
Invited speaker, Scientific Advisory Board meeting of IAOMT, Atlanta , Georgia , 21 April 2007 .
Presenter to KEDFA, Frankfurt , KY April 26 2007 .
Invited speaker American College of Academic Medicine, Chicago , IL 10 May 2007 .
Invited speaker Michigan Autism conference. Iron Mountain , MI 19 May 2007. Invited speaker Autism One conference, Chicago , IL 25 May 2007 .
Invited speaker Moms Against Mercury, Atlanta , GA 6-7 June 2007.
Invited presenter Meeting with FDA commissioner of science, Washington , DC . 22 June 2007 .
Honored guest, Florida Autims Association Fund Raiser. Ponte Verde Beach , FL 28 June 2007 .
Meeting with Dean Michael Kotlikoff, Cornell U. School Veterinary Medicine. 6-7 July 2007.
Invited speaker Boulderfest Autism conference, Boulder , CO 12 July 2007 .
Invited speaker United States Autism and Asperger’s Association, Denver, CO. 7-9 August 2007.
Invited speaker West Virgina Medical Group, Dr. John MacCallum, Charlottesvile , WV . 17 August, 2007 .
Expert witness Yost Law firm. Autism parents vs pharmaceutical firms. 20-21 August 2007.
Invited speaker Stelior Autism conference Tarter , Estonia 29-31 August, 2007
Invited speaker International Academy of Oral and Medical Toxicology. Las Vegas , NV 7-8 September 2007.
Invited speaker Northern Kentucky University , Dept. Chemistry, Ft. Morgan , KY 19 September 2007 .
Invited speaker Great Plains Autism conference, Kitchener , Ontario Canada 28-29 September.

SERVICE TO DEPARTMENT, COLLEGE AND UNIVERSITY:

1975-1979 Faculty Senate
Biological Interdepartmental Seminar Committee
University Grievance Procedure Committee
College of Agriculture Teaching Improvement Committee
College of Agriculture Academic Planning Committee
Faculty Senate Nominating Committee
Division of Biochemistry Undergraduate Teaching Committee
Division of Biochemistry Graduate Program Committee
University Research Coordination Committee
Chairman of the Graduate Committee, Biochemistry Department
1979-1982 College of Agriculture Tenure and Promotion Committee
1979 College of Agriculture Dean Search Committee
1981 Vice-President for Research Search Committee
1981 College of Human Medicine Evaluation Committee
1981-1982 Biomedical Research Funding Committee
1982 Chairman, Department of Zoology and Physiology Review Committee
1986 Research Committee College of Medicine
Ad Hoc Committee to Review Center on Aging
Ad Hoc Medical Center Research Advisory Committee
Working Group for Biotechnology Center
Center for Pharmaceutical Science and Technology Advisory Committee
College of Pharmacy Graduate Program
College of Pharmacy Research and Seminar
1987 Markey Cancer Center Internal Advisory Committee
College of Medicine Research Committee
Tobacco and Health Advisory Committee
1988 College of Pharmacy BRSG Committee, Tenure and Promotion
1989 Chairman, College of Medicine BRSG Committee
Member, Tobacco & Health Advisory Committee
Member, Markey Cancer Center Advisory Committee
1990 Chairman, College of Medicine BRSG Committee
1991-1992 Member, Intellectual Properties Committee
Member, Search Committee Cancer Center Director
Member, Cancer Center Advisory Committee Member, Search Committee Diagnostic Radiology Chair
Member, Academic Area Committee, Biological Sciences
1993-1995 Chair, Research and Seminar Committee
Member, Appointment, Tenure and Promotion Committee
1996-1997 Chair, Graduate Program task force, College of Pharmacy
Chair, Physical Plant section, College of Pharmacy self-study
University Chemical Safety Committee
College of Medicine Academic Council
College of Pharmacy Tenure and Promotion Committee

PUBLICATIONS (REFEREED JOURNALS)

1. Haley, B. and Yount, R. Gamma-fluoradenosine Triphosphate.Synthesis, Properties and Interaction with Myosin and Heavy Meromyosin. Biochemistry II, 2863-2871 (1972).

2. Haley, B., Yount and Hoffman, J. Selective Inhibition of Divalent Metal Ion Requiring ATPase Activity of Human Red Cell Ghost by an Analog of ATP. The Physiologist 16, 333-334 (1973).

3. Haley, B. and Hoffman, J. Interactions of Photo-Affinity ATP Analog with Cation-Stimulated ATPase Activities of Human Red Cell Ghost. Proc. Natl. Acad. Sci. 71, 3367-3371 (1974).

4. Staros, J.V., Haley, B. and Richards, F.M. Human Erythrocytes and Resealed Ghost: A Comparison of Membrane Topology. J. Biol. Chem. 249, 5004-5007 (1974).

5. Pomerantz, A., Rudolph , S.A. , Haley, B. and Greengard, P. Photoaffinity Labeling of a Protein Kinase from Bovine Brain with 8-Azido-adenosine-3', 5'-monophosphate. Biochemistry 14, 3852-3857 (1975).

6. Haley, B. Photoaffinity Labeling of cAMP Binding Sites of Human Red Blood Cell Membranes. Biochemistry 14, 3852-3857 (1975).

7. Staros, J.V., Richards, F.M. and Haley, B. Photochemical Labeling of the Cytoplasmic Surface of the Membranes of Intact Human Erythrocytes. J. Biol. Chem. 250, 8174-8178 (1975).

8. Malkinson, A.M., Krueger, B.V., Rudolph, S.A., Casnelli, J.E., Haley, B. and Greengard, P. Widespread Occurence of a Specific Protein in Vertebrate Tissues and Regulation by cAMP of its Endogenous Phosphorylation and Dephosphorylation. Metabolism 24, 331-341 (1975).

9. Haley, B. Photoaffinity Labeling of Adenosine 3', 5'-Cyclic Monophosphate Binding Sites. Methods in Enzymology, Jacoby and Wilchek, Editors. V 46, pp. 339-346 (1976).

10. Owens, J.R. and Haley, B.E. A Study of Adenosine 3', 5'-Cyclic Monophosphate Binding Sites of Human Erythrocyte Membranes Using 8-Azido-adenosine-3'-5' Cyclic Monophosphate. J. Supra. Mole. Structure 5, 91-102 (1976).

11. Skare, K., Black, J.L., Pancoe, W.L. and Haley, B. Determination of the Cellular Location of Cyclic Nucleotide Binding Sites Using 8-Azido-adenosine-3', 5'-monophosphate, A Photoaffinity Probe. Arch. Biochem. Biophy. 180, 409-415 (1977).

12. Lau, E., Haley, B. and Barden, R. Interactions of a Photoaffinity Analog of CoA with CoA Enzymes. Biochemistry 16, 2581-2585 (1977).

13. Owens, J.R. and Haley, B. A Study of Adenosine 3', 5'-Cyclic Nucleotide Binding Sites of Human Erythrocyte Membranes Using 8-Azido-adenosine 3'-5'-Cyclic Monophosphate. Cell Shape and Surface Architecture: Progress in Clinical and Biological Research 17, 65-76 (1977)

14. Lau, E.P., Haley, B. and Barden, R. The 8-Azidoadenine Analog of S-Benzoyl (3'-dephospho) Coenzyme A-A Photoaffinity Label for Acyl CoA; Glycine N-Acyltransferase. Biochem. Biophys. Res. Commun 76, 843-849 (1977).

15. Geahlen, R.T. and Haley, B. Interactions of a Photoaffinity Analog of GTP with the Proteins of Microtubules. Proc. Natl. Acad. Sci. 74, 4375-4377 (1977).

16. Owens, J.R. and Haley, B. Use of Photoaffinity Nucleotide Analogs to Determine the Mechanism of ATP Regulation of a Membrane Bound, cAMP Activated Protein Kinase. J. Supra. Mole. Structure 9, 57-68 (1978).

17. Czarnecki, J., Geahlen, R.T. and Haley, B. Synthesis and Use of Azido Photoaffinity Analogs of Adenine and Guanine Nucleotides. Methods in Enzymology 56, 642-653 (1979).

18. Marcus, F. and Haley, B. Inhibition of Fructose 1,6-biphosphatase by the Photoreactive AMP Analog, 8-Azido-AMP. J. Biol. Chem. 254, 259-261 (1979).

19. Geahlen, R., Haley, B. and Krebs, E.G. Synthesis and Use of 8-azidoguanosine 3', 5'-cyclic Monophosphate as a Photoaffinity Label for Cyclic GMP-dependent Protein Kinase. Proc. Natl. Acad. Sci. 76, 2213-2217 (1979).

20. Geahlen, R. and Haley, B. Use of GTP Photoaffinity Probe to Resolve Aspects of the Mechanism of Tubulin Polymerization. J. Biol. Chem. 254, 11982-11987 (1979).

21. Haley, B. Application of Photoaffinity Nucleotide Analogs to Biological Membrane Research. Selected Aspects of Cancer-Related Protein, Carbohydrate, Lipid and other Biochemistry, International Cancer Research Data Bank, p. 87 (1979).

22. Owens, J. and Haley, B. Mechanism of MgATP Regulation of Membrane Bound Type I cAMP Activated Protein Kinase. Transmembrane Signaling. Alan R. Liss, Inc. New York , New York , pp. 149-160 (1979).

• Forrester, I.T., P.K. Schoff, B.E. Haley and R.G. Atherton. Determination of Protein Kinase Activity in Intact Mammalian Sperm. J. of Andrology 1, 70 (1980).

24. Briggs, F. Norman, Al-Jumaily, Walid and Haley, Boyd. Photoaffinity Labeling of the (Ca +Mg) ATPase of Skeletal and Cardiac Sarcoplasmic Reticulum with [ 32P-]-8-Azido ATP. Cell Calcium 1, 205-215 (1980).

25. Hoyer, P., Owens, J.R. and Haley, B.E. Use of Nucleotide Photoaffinity Probes to Elucidate Molecular Mechanisms of Nucleotide Regulated Phenomena. Annals of New York Academy of Science 346, 280-301 (1980).

26. Takemoto, D.J., B.E. Haley, J. Hanse, P. Pinbett and L.J. Takemoto. GTPase from Rod Outer Segments: Characterization by Photoaffinity Labeling and Tryptic Peptide Mapping. Biochem. Biophys. Res. Commun. 102, 341-347 (1981).

27. Leichtling, B.H., Coffman, D.S., Yaeger, E.S., Rickenberg, H.V., Al-Jumaily, W. and Haley, B.E. Occurrence of the Adenylate Cyclase "G-Protein" in Membranes of Dictyostelium discoidium, Biochem. Biophys. Res. Commun. 102, 1187-1195 (1981).

28. Schoff, P.K., Forester, I.T., Haley, B.E. and Atherton, R. A Study of cAMP Binding Proteins on Intact and Distrupted Sperm Cells Using 8-Azidoadenosine-3', 5'-Cyclic Monophosphate. J. Supra. Molecular Structure 19, 1-15 (1982).

29. King, M.M., Carlson, G. and Haley, B.E. Photoaffinity-Labeling of the Subunit of Phosphorylase Kinase by 8-Azidoadenosine-5'-Triphosphate and its 2', 3' -Dialdehyde Derivative. J. Biol. Chem. 257, 14058-14065 (1982).

30. Potter, R. and Haley, B.E. Photoaffinity Labeling of Nucleotide Binding Sites with 8-Azidopurine Analogs. Meth. Enzymol. 91, 613-633 (1982).

31. Hoyer, P.B. and Haley, B.E. Utilization of Nucleotide Photoaffinity Probes to Study Protein-Nucleotide Interactions in Cell Fractions. J. Cellular Biochemistry, submitted. (1983)

32. Haley, Boyd. Development and Utilization of 8-Azidopurine Nucleotide Photoaffinity Probes. Federation Proceedings 42, 2831-2836 (1983).

33. Khatoon, S., Atherton, R. Al-Jumaily, W. and Haley, B.E. Use of Nucleotide Photoaffinity Probes to Study Hormone Action. Biology of Reproduction 28, 61-73 (1983).

34. Kaiser, I.I., Kladianos, D.M., Van Kirk, E.A., and Haley, B.E. Photoaffinity Labeling of catechol-o-methyltransferase with 8'-Azido-S-adenosylmethionine. J. Biol. Chem. 258, 1747-1751 (1983).

35. Abraham, K., Haley, B. and Modak, M. Biochemistry of Terminal Deoxynucleotidyl Transferase: 8-Azido ATP as A Substrate Binding Site-Directed Photoaffinity Labeling Prob. Biochemistry 22, 4197-4203 (1983).

36. Haley, B.E., Ponstingl, H. and Doenges, K.H. Photoaffinity Labeling of Pure Tubulin Using 8-Azidoguanosine triphosphate at the b -Subunit. Hoppe- Seylers J. Physiol. Chem. 364, 1137 (1983).

37. Woody, A.M., Vader, C.R., Woody, R.W. and Haley, B.E. Photoaffinity Labeling of DNA-dependent RNA polymerase from E. coli with 8-azidoadenosine-5'-triphosphate. Biochemistry 23, 2843-2848 (1984).

38. Owens, J.R. and Haley, B.E. Synthesis and Utilization of [5'- 32P]-8-Azidoguanosine-3'-phosphate-5'-phosphate: Photoaffinity Studies on Cytosolic Proteins of E. coli. J. Biol. Chem. 259, 14843-14848 (1984).

39. Pfister, K.K. , Haley, B.E. and Witman, G.B. The Photoaffinity Probe 8-azidoadenosine-5'-triphosphate. Selectivity Labels the Heavy Chain of Chlamydomonas 12S Dynein. J. Biol. Chem. 259, 8499-8504 (1984).

40. Atherton, R.W., Khatoon, S., Schoff, P.K. and Haley, B.E. A Study of Rat Epididymal Sperm Adenosine-3', 5'-monophosphate-dependent Protein Kinase: Maturation Differences and Cellular Location. Biol. of Reproduction 32, 155-172 (1985).

41. McMurray, M.M., Hansen, J.S., Haley, B.E., Takemoto, D.J. and Takemoto, L.J. Interspecies Conservation of Retinal Guanosine-5'-triphosphatase: Characterization by Photoaffinity Labeling and Tryptic Peptide Mapping. Biochemical Journal 225, 227-232 (1985).

42. Khatoon, S., Haley, B.E. and Atherton, R.W. A Comparative Analysis of cAMP-dependent Protein Kinase Regulatory Subunits in Sea Urchin and Rat Sperm. J. Andrology 6, 251-260 (1985).

43. DeBortoli , M.E. , Issa, H.A., Haley, B.E. and Cho-Chung, Y.S. Elevated Levels of p2l ras Protein in Hormone-Dependent Mammary Carcinomas of Humans and Rodents. Bioch. Biophys. Res. Commun. 127, 699-709 (1985).

44. Evans, R., Haley, B. and Roth, D. Photoaffinity Labeling of a Viral Induced Protein from Tobacco. J. Biol. Chem. 260, 7800-7804 (1985).

45. Nunamaker, R.A., Wilson , W.T. and Haley, B.E. Electrophoretic Detection of Africanized Honey Bees ( Apis mellifera scutellata) in Guatemala and Mexico Based on Malate Dehydrogenase Allozyme Patterns. Journal of the Entomological Society 57, 622-631 (1985).

46. Pfister, K.K., Haley, B.E. and Witman, G.B. Labeling of Chlamydomonas 18S Dynein Polypeptides by 8-Azidoadenosine 5'-Triphosphate, a Photoaffinity Analog of ATP. J. Biol. Chem. 260, 12844-12850 (1985).

47. Hoyer, P.B., Fletcher, P. and Haley, B.E. Synthesis of 2', 3'-0-(2,4,6,-trinitrocyclohexadienylidine) guanosine 5'-Triphosphate and study of its Inhibitory Properties with Adenylate Cyclase. Arch. Biochem. Biophys. 245, 368-378 (1986).

48. Evans, R.K., Johnson, J.D. and Haley, B.E. 5'-Azido-2'-deoxyuridine-5'-triphosphate: A Novel Photoaffinity Labeling Reagent and Tool for the Enzymatic Synthesis of Photoactive DNA. Proc. Natl. Acad. Sci. USA. 83, pp. 5382-5386 (1986).

49. Jeganathan, A., Richardson , S.K., Mani, R.S., Haley, B.E. and Watt, D.S. Selective Reactions of Azide-substituted a -Diazoamides with Olefins and Alcohols Using Rhodium (II) Catalysts. J. Org. Chem. 51, 5362-5367 (1986).

50. Malkinson, A.M., Haley, B.E., Macintyre, B.E. and Buthy, M.S. Changes in Pulmonary Adenosine Triphosphate Binding Proteins Detected by Nucleotide Photoaffinity Labeling Following Treatment of Mice with the Tumor-Modulatory Agent Butylated Hydroxytoluene. Cancer Res. 46, 4626-4630 (1986).

51. Evans, R.K. and Haley, B.E. Synthesis and Biological Properties of 5-Azido-2'-deoxyuridine-5'-triphosphate: A Photoactive Nucleotide Suitable for Making Light Sensitive DNA. Biochemistry 26, 269-276 (1987).

52. Richardson , S.K., Jeganathan, A., Mani, R.S., Haley, B.E. and Watt, D.S. Synthesis and Biological Activity of C-4 and C-15 Aryl Azide Derivatives of Anguidine. Tetrahedron Letters 43, 2925 (1987).

53. Droms, K.A., Haley, B.E. and Malkinson, A.M. Decreased Incorporation of the Photoaffinity Probe [ g 32 32 P]-8N 3 GTP into a 45KD Protein in Lung Tumors. Bioch. Biophys. Res. Commun. 144, 591-597 (1987).

54. Karpel, R.L., Levin, V.Y. and Haley, B.E. Photoaffinity Labeling of T4 Bacteriophage 32Protein. J. Biol. Chem. 262, 9359-66 (1987).

55. Suhadolnik, R.J., Li, Shi Wu, Sobol, Jr. R.W., and Haley, B.E. 2-and 8-Azido Photoaffinity Probes. II. Studies on the Binding Process of 2-5A Synthetase. Biochemistry 27, 8846-8851 (1988).

56. Suhadolnik, R.J., Kariko, K., Sobol, Jr., R.W., Shi Wu, Richenbach, N.L. and Haley, B.E. 2- and 8-Azido Photoaffinity Probes. I. Enzymatic Synthesis, Characterization and Biological Properties of 2- and 8-Azido Photoprobes of 2-5A & Photolabeling of 2-5A Binding Proteins. Biochemistry 27, 8840-8846 (1988).

57. Droms, K.A., Haley, B.E., Smith, G.J. and Malkinson, A.M. Decreased Photolabeling of G s a With [ a - 32P]8N 3-GTP in Tumorigenic Lung Epithelial Cell Lines: Association with Decreased Hormone Responsiveness and Loss of Contact-Inhibited Growth. Experimental Cell Research 182, 330-339 (1989).

58. Francis, B., Overmeyer, J., John, W., Marshall, E. and Haley, B. Prevalence of Nucleoside Diphosphate Kinase Autophosphorylation in Human Colon Carcinoma versus Normal Colon Homogenates. Molecular Carcinogenesis 2, 168-178 (1989).

59. King, S.M., Haley, B.E. and Witman, G.B. Structure of the a and b Heavy Chains of the Outer Arm Dynein from Chlamydomonas Flagella. J. Biol. Chem. 264, 10210-10218 (1989).

60. Khatoon, S., Campbell , S.R., Haley, B.E. and Slevin, J.T. Aberrant GTP b -Tubulin Interaction in Alzheimer's Disease. Annals of Neurology 26, 210-215 (1989).

61. Lawson, S.G., Mason, T.L., Sabin, R.D., Sloan , M.E. , Drake, R.R., Haley, B.E. and Wasserman, B.P. UDP-Glucose: (1,3)-B-Glucan Synthase from Daucas carota L.: Characterization, Photoaffinity Labeling and Solubilization. Journal of Plant Physiology 90, 101-108 (1989).

62. Lewis, C.T., Haley, B.E. and Carlson, G.M. Formation of an Intramolecular Cystine Disulfide During the Reaction of 8-Azido-GTP with Cytosolic Phosphoenolpyruvate Carboxykinase (GTP) Causes Inactivation without Photolabeling. Biochemistry 28, 9248-9255 (1989).

63. Ho, L.T., Nie, Z.M., Mende, T.J., Richardson , S., Chavan, A., Kolaczkowska, E., Watt, D.S., Haley, B.E. and Ho, R.J. Modification of Adenylate Cyclase by Photoaffinity Analogs of Forskolin. J. Second Messengers and Phosphoproteins 12, 209-223 (1989).

64. Wasserman, B.P., Read, S.M., Frost, D.J., Mason, T.L., Drake, R.R. and Haley, B.E. Potential use of Affinity Labels in Subunit Identification Studies of (1,3)- b -Glucan Synthase. J.Applied Polymer Science Symposium (Proceeding of the Tenth Cellulose Conference, Syracuse , NY ). C. Schuerch and T. Timell, Eds. 43, 827-837 (1989).

65. Drake, R.R., Evans, R.K., Wolf, M.J. and Haley, B.E. Synthesis and Properties of 5-Azido-UDP-Glucose: Development of Photoaffinity Probes for Nucleotide Diphosphate Sugar Binding Sites. J. Biol. Chem. 264, 11928-11933 (1989).

66. Dholakia, J.N., Francis, B.R., Haley, B.E. and Wahba, A. Photoaffinity Labeling of the Rabbit Reticulocyte Guanine Nucleotide Exchange Factor and Eukaryotic Initiation Factor 2 with 8-Azidopurine Nucleotides. J. Biol. Chem. 264, 20638-20642 (1989).

67. Campbell,S., Kim, H., Doukas, M. and Haley, B. Photoaffinity Labeling of ATP and NAD + Binding Sites on Recombinant Human Interleukin-2. Proc. Natl. Acad. Sci. 87, 1243-1246 (1990).

68. Kim, H. and Haley, B. Synthesis and Properties of 2-Azido-NAD +: A Study of Interactions with Glutamate Dehydrogenase. J. Biol. Chem. 265, 3636-3641 (1990).

69. Drake, R., Palamarczyk, G., Haley, B. and Lennarz, W.J. Evidence for the Involvement of a 35-kDa Membrane Protein in the Synthesis of Glucosylphosphoryldolichol. Bioscience Reports 10, 61-68 (1990).

70. Marchase, R.B., Richardson , K.L., Srisomsap, C., Drake, R. and Haley, B.E. Resolution of Phosphoglucomutase and the 62 kDa Acceptor for the Glucosylphosphotransferase. Arch. Biochim. Biophys. 280, 122-129. (1990).

71. Salvucci , M.E. and Haley, B.E. Photoaffinity Labeling of Ribulose Bisphosphate Carboxylase/Oxygenase With 8-Azidoadenosine 5'-Triphosphate. Planta 181, 287-295 (1990).

72. Salvucci , M.E. , Drake, R., Broadbent, K.P., Haley, B.E., Hanson, K.R. and McHale, N.A. Identification of the 64 Kilodalton Chloroplast Stromal Phosphoprotein as Phosphoglucomutase. Plant Physiology 93, 105-109 (1990).

73. Frost, D.J., Read, S.M., Drake, R., Haley, B.E. and Wasserman, B.P. Identification of the UDPG Binding Polypeptide of (1,3)- b -Glucan Synthase From A Higher Plant by Photoaffinity Labeling with 5-AzidoUDP-Glucose. J. Biol. Chem. 265, 2162-2167 (1990).

74. Lin, F.C., Brown, R.M. Jr., Drake, R.R. and Haley, B.E. Characterization of Cellulose Synthase Catalytic Subunit of Acetobacter xylinum Using 5-Azido-UDP-glc, A Photoaffinity Probe. J. Biol. Chem. 265, 4782-4784 (1990).

75. Salvucci , M.E. , Drake, R.R., and Haley, B.E. Purification and Photoaffinity Labeling of Sucrose Phosphate Synthase from Spinach Leaves. Arch. Biochem. Biophys. 281, 212-218 (1990).

76. Chavan, A.J., Kim, H., Haley, B.E., and Watt, D.S. A Photoactive Phosphonamide Derivative of GTP for the Identification of the GTP Binding Domain of b -Tubulin. Bioconjugate Chemistry, 1, No. 5, 337-344 (1990).

77. Kwiatkowski, S., Crocker, P.J., Chavan, A.J., Nobuyuki, I. , Haley, B.E. and Watt, D.S. Thiazolidine and Thiazoline Derivatives of 3-Aryl 3-Trifluormethyl Diazirines for the Preparation of Fluorescent or 35S-Radiolabeled Photoaffinity Probes. Tetrahedron Lett, 31, 2093-2096 (1990).

• Palamarczyk, G., Drake, R., Haley, B. and Lennarz, W.J. Evidence that the Synthesis of Glucosylphosphoryl Dolichol in Yeast Involves a 35 kDa Membrane Protein. Proc. Natl. Acad. Sci. 87, 2666-2670 (1990).
•  
• King, S., Kim, H., and Haley, B. Strategies and Reagents for Photoaffinity Labeling of Mechanochemical Proteins. Meth. Enzymol. 196, 449-466 (1991).
•  
• Kim, H. and Haley, B. Identification of Peptides in the Adenine Ring Binding Domain of Glutamate and Lactate Dehydrogenase Using 2-AzidoNAD +. Bioconjugate Chemistry 2, 1142-147 (1991).
•  
• Mann, D., Haley, B., and Greenberg, R. Photoaffinity Labeling of Atrial Natriurtic Factor Analog Atriopeptin III woith [ g 32 P]8N 3GTP. Peptide Research 4, #2, 79-83 (1991).
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• Drake, R.R., Zimniak, P., Haley, B.E., Lester, R., Elbein, A.D. and Radominska, A. Synthesis and Characterization of5-Azido-UDP-Glucuronic Acid. J. Biol. Chem., 266, 23257-23260 (1991).
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83. Drake, R.R., Zimniak, P., Haley, B.E., Lester, R., Elbein, A.D. and Radominska, A. Synthesis and Characterization of5-Azido-UDP-Glucuronic Acid. J. Biol. Chem., 266, 23257-23260 (1991).

84. Hiestand, D., Haley, B., and Kindy, M. Role of Calcium inInactivation of Calcium/Calmodulin Dependent Protein Kinase II After Cerebral Ischemia. Journal of the Neurological Sciences, 113, 31-37 (1992).

85. Salvucci, M., Chavan, A. and Haley, B. Identification of Peptides for the Adenine Binding Domains of ATP and AMP in Adenylate Kinase: Isolation of Photoaffinity Labeled Peptides by Metal Chelate Chromatography. Biochemistry 31 4479-4487 (1992).

86. Shoemaker, M., Lin, P.C., and Haley, B. Identification of the Guanine Binding Domain Peptide of the GTP Binding Site of Glucagon. Protein Science 1, 884-891 (1992).

87. Doukas, M., Chavan, A., Gass, C., Boone, T. and Haley, B. Identification and charaterization of a Nucleotide Binding Site on Recombinant Murine Granulocyte/Macrophage-Colony Stimulating Factor. Bioconjugate Chemistry 3, 484-492 (1992).

88. Segal, A., West, I. , Wientjes, F., Nugent, J., Chavan, A., Haley, B., Garcia, R., Rosen, H. and Scrace, G. Cytochrome b- 245 is a Flavocytochrome Containing FAD and the NADPH Binding Site of the Microbicidal Oxidase of Phagocytes. Biochem. J. 284, 781-788 (1992).

89. Hammond, D., Haley, B. and Lesnaw, J. Identification and Characterization of Serine/Threonine Protein Kinase ActivityIntrinsic to the L Protein of Vesicular Stomatitis Virus New Jersey . Journal of General Virology 73, 67-75 (1992)

90. Chavan, A., Nemoto, Y., Narumiya, S., Kozaki, S., and Haley, B. NAD + Binding Site of Clostridium botulinum C3 ADP-ribosyltransferase: Identification of Peptide in the Adenine Ring Binding Domain using 2-Azido NAD +. J. Biol. Chem. 267, 14866-14870 (1992).

91. Gunnersen, D.J. and Haley, B.E. Detection of Glutamine Synthetase in the Cerebrospinal Fluid of Alzheimer's Diseased Patients: A Potential Diagnostic Biochemical Marker. Proc. Natl. Acad. Sci. USA, 89 pp. 11949-11953 (1992).

92. Shoemaker, M., and Haley, B. Identification of a Guanine Binding Domain Peptide of the GTP Binding Site of Glutamate Dehydrogenase: Isolation with Metal-Chelate Affinity Chromatography. Biochemistry 32, 1883-1890 (1993).

93. Churn, S.B., Sankaran, B., Haley, B.E. and Delorenzo, R.J. Ischemic Brain Injury Selectively Alters ATP Binding of Calcium and Calmodulin-Dependent Protein Kinase-II. Biochem. Biophys. Res. Comm. 193:3, 934-940 (1993).

94. Salvucci, M., Rajagopalan, K., Sievert, G., Haley, B. and Watt, D. Photoaffinity Labeling of Rubisco Activase with ATP -g -benzophenone: Identification of the ATP g -Phosphate Binding Domain J. Biol. Chem. 268, 14239-14244 (1993).

95. Rajagopalan, K., Chavan, A., Haley, B. and Watt, D. Bidentate Cross-Linking Reagents: Non-Hydrolyzable Nucleotide Photoaffinity Probes with Two Photoactive Groups J. Biol. Chem. 268, 14245-14253 (1993).

96. Trad, C., Chavan, A., Clemens, J., and Haley, B. Identification and Characterization of an NADH Binding Site of Prolactin with 2-Azido-NAD + Arch. Biochem. Biophys. 304, 58-64 (1993).

97. Chavan, A., Ensor, C., Wu, P., Haley, B. and Tai, H. Photoaffinity Labeling of Human Placental NAD +-Linked 15-Hydroxyprostaglandin Dehydrogenase with [ a 32 P]-2N 3NAD +: Identification of a Peptide in the Adenine Ring Binding Domain J. Biol. Chem. 268, 16437-16442 (1993).

98. Chavan, A., Richardson, S., Kim, H., Haley, B. and Watt, D. Forskolin Photoaffinity Probes for the Evaluation of Tubulin Binding Sites Bioconjugate Chem. 4, 268-274 (1993).

99. Duhr, E.F., Pendergrass, J. C., Slevin, J.T., and Haley, B. HgEDTA Complex Inhibits GTP Interactions With The E-Site of Brain b -Tubulin Toxicology and Applied Pharmacology 122, 273-288 (1993).

100. Jayaram, B. and Haley, B. Identification of Peptides Within the Base Binding Domains of the GTP and ATP Specific Binding Sites of Tubulin. J. Biol. Chem. 269 (5) 3233-3242 (1994).

101. A. Chavan, B. Haley, D. Volkin, K. Marfia, A. Verticelli, M. Bruner, J. Draper, C. Burke and R. Middaugh. Interaction of Nucleotides with Acidic Fibroblast Growth Factor (FGF-1). Biochemistry 33,7193-7202 (1994).

102. Logan , J., Hiestand, D., Daram, P., Huang, Z., Muccio, D., Hartman, J., Haley, B., Cook, W., and Sorscher, E. Cystic Fibrosis Transmembrane Conductance Regulator Mutations That Disrupt Nucleotide Binding. J. Clin. Invest. 94, 228-236 (1994).

103. Olcott, M. and Haley, B. Identification of Two Peptides From the ATP-Binding Domain of Creatine Kinase. Biochemistry, 33, 11935-11941 (1994).

104. Bhattacharyya, A., Chavan, A., Shuffett, M., Haley, B. and Collins, D. Photoaffinity Labeling of Rat Liver Microsomal 5 a -Reductase by 2-Azido-NADP +. Steroids 59, 634-641 (1994).

105. Salvucci, M., Chavan, A., Klein, R., Rajagopalan, K. and Haley, B. Photoaffinity Labeling of the ATP Binding Domain of Rubisco Activase and a Separate Domain Involved in the Activation of Ribulose-1,5-Bisphosphate Carboxylase/Oxygenase. Biochemistry 33, 14879-14886 (1994).

106. Pendergrass, J.C. and Haley, B.E. Mercury-EDTA Complex Specifically Blocks Brain b -Tubulin-GTP Interactions: Similarity to Observations in Alzheimer”s Disease. pp98- 105 in Status Quo and Perspective of Amalgam and Other Dental Materials (International Symposium Proceedings ed. by L. T. Friberg and G. N. Schrauzer) Georg Thieme Verlag, Stuttgart-New York (1995).

107. Doukas, M., Chavan, A., Gass, C., Nickel, P., Boone, T. and Haley, B. Inhibition of GM-CSF Activity by Suramine and Suramin Analogues is Correlated to Interaction with the GM-CSF Nucleotide Binding Site. Cancer Research 55:5161-5163 (1995).

108. Bhattacharyya, A. K., Chavan, A.J., Haley, B., Taylor , M.F., and Collins, D.C. Identification of the NADP(H) Binding Site of Rat Liver Microsomal 5 a -Reductase (Isozyme-1): Purification of a Photolabeled Peptide Corresponding to the Adenine Binding Domain. Biochemistry 34, 3663-3669 (1995)

109. Chavan, A., Gass, C., Haley, B., Boone, T. and Doukas, M. A. Identification of N-Terminus Peptide of Human Granulocyte/Macrophage Colony Stimulating Factor as the Site of Nucleotide Interaction. Biochem. Biophys. Res. Commun. 208,#1 390-396 (1995).

110. Shoemaker, M., and Haley, B. Identification of the Adenine Binding Domain Peptides of the ADP Binding Site of Glutamate Dehydrogenase. Bioconjugate Chemistry 7, 302-310 (1996).

111. Rajagopalan, K., Pavlinkova, G., Levy, S., Pokkuluri, R., Schiffer, M., Haley, B., and Kohler, H. Novel Unconventional Binding Site in the Variable Region of Immunoglobulins. Proc. Natl. Acad. Sci. 93, 6019-6024 (1996).

112. Pavlinkova, G., Rajagopalan, K., Muller, S., Chavan, A., Sievert, G., Lou, D., O’Tolle, C., Haley, B., and Kohler, H. Site-Specific Photobiotinylation of Immunoglobins, Fragments and Light Chain Dimers. J. Immunological Methods 201, 77-88 (1997).

• Pendergrass, J.C. and Haley, B.E. Inhibition of Brain Tubulin-Guanosine 5’-Triphosphate Interactions by Mercury: Similarity to Observations in Alzheimer’s Diseased Brain. In Metal Ions in Biological Systems V34, Mercury and Its Effects on Environment and Biology, Chapter 16. Edited by H. Sigel and A. Sigel. Marcel Dekker, Inc. 270 Madison Ave. , N.Y. , N.Y. 10016 (1996).
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• McGuire, M., Carroll, L. J., Yankie, L., Thrall, S. H., Dunaway-Mariano, D., Hertzberg, O., Jayaram, B. and Haley, B. Determination of the Nucleotide Binding Site within Clostridium symbiosum Pyruvate Phosphate Dikinase by Photoaffinity Labeling, Site-Directed Mutagenesis, and Structural Analysis. Biochemistry 35, 8544-8552 (1996).
•  
• Kohler, H., Pavlinkova, G., and Haley, B. Immunoglobulin Nucleotide Binding Site: A Possible Superantigen Receptor. In Human B Cell Superantigens, edited by Moncei Zouali, Chapter 13, pp 189-194 (1996).
• Sankaran, B., Chavan, A. and Haley, B. Identification of Adenine Binding Domain Peptides of the NADP + Active Site within Porcine Heart NADP +-Dependent Isocitrate Dehydrogenase. Biochemistry 35, 13501-13510 (1996).
•  
• Sankaran, B., Clemens, J., and Haley, B. A Comparison of Changes in Nucleotide-Protein Interactions in the Striatal, Hippocampus and Paramedian Cortex After Cerebral Ischemia and Reperfusion: Correlations to Regional Vulnerability. Molecular Brain Research 47, 237-250 (1997).
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• Hensley, K., Cole, P. ,Aksenov, M., Aksenova, M., Bummer, P.E., Carney, J.M., Haley, B.E., and Butterfield, D.A. Oxidatively-Induced Structural Alteration of Glutamine Synthetase Assessed by Analysis of Spin Label Incorporation Kinetics. J. of Neurochemistry 68, 2451-2457 (1997).
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• Pendergrass, J. C., Haley, B.E., Vimy, M. J., Winfield , S.A. and Lorscheider, F.L. Mercury Vapor Inhalation Inhibits Binding of GTP to Tubulin in Rat Brain: Similarity to a Molecular Lesion in Alzheimer’s Disease Brain. Neurotoxicology 18(2), 315-324 (1997).
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• Olcott, M.C. and Haley, B.E. Identification of an Adenine-nucleotide Binding Site on Interferon- a 2. Eur. J. Biochem. 247/3, 762-769 (1997).
•  
• David, S., Shoemaker, M., and Haley, B. Abnormal Properties of Creatine kinase in Alzheimer’s Disease Brain: Correlation of Reduced Enzyme Activity and Active Site Photolabeling with Aberrant Cytosol-Membrane Partitioning. Molecular Brain Research accepted (1997).

• Holmes, A.S., Blaxill, M.F. and Haley, B. Reduced Levels of Mercury in First Baby Haircuts of Autistic Children. International J. of Toxicology, 22:1-9, 2003

• Haley, B. The Relationship of the Toxic Effects of Mercury to Exacerbation of the Medical Condition Classified as Alzheimer’s Disease. Nordic J. of Biological Medicine, June-July 2003

• Haley, B. Mercury Toxicity: Genetic Susceptibility and Synergistic Effects. Medical Veratis 2 (2005) 1-8.

• J. Mutter, J. Naumann, R. Schneider, H. Walach and B. Haley Mercury and Autism: Accelerating Evidence? Neuroendcrinology Letters Vol 26 No. 5, October 2005.

• Wojcik, D.P., Godfrey , M.E. Christie, D. and Haley, B.E. Mercury Toxicity Presenting as Chronic Fatigue, Memoray Impairment and Depression: Diagnosis, Treatment, Susceptibility and Outcomes in a New Zealand General Practice Setting (1994-2006) Neuro. Endocrinol. Letters Aug5:27(4) 2006 416-423.

127. Haley, B. A look at the 2006 FDA hearing on the safety of dental amalgams and possible toxicological concerns Medical Veratis (2006) October 1-5.

128. Haley, B. The relationship of the toxic effects of mercury to exacerbation

of the medical condition classified as Alzheimer’s disease. Medical Veritas 4 (2007) 1510–1524.

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