WAVE - Vaccine Ingredients Latex

Vaccine Ingredients
Latex

Chemical Analysis

Latex:

Latex often contaminates vaccine solutions by interacting with the syringe plungers, vial stopper or seal. Latex contains numerous polypeptides, many of which may act as allergens; case reports describe various immediate-type ...more

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Scientific Literature Only

1. "Allergic reaction to vaccines should be investigated"
"Some people have an allergic reaction after having an immunization, an experience that often -- and quite naturally -- leads to an avoidance of any future immunizations... However, when a serious reaction occurs, the patient should be evaluated by an allergist to determine the culprit allergen. This can be done through allergy testing. Vaccine components that could cause reactions include gelatin or egg protein, yeast, latex from the syringe plungers, neomycin and thimerosal."
Shari Roan, LosAngeles Times -- 10/9/2009

2. "Latex Allergy Linked to Adverse Reaction to Swine Flu Shot"
"Health officials in Australia, where mass vaccination against swine flu began eight days ago, said a person with an allergy to latex developed a reaction to the shot."
Json Gale, Bloomberg.com -- 10/7/2009

3. " Israeli Health Ministry halts flu vaccine after three people die"
"Israel's Health Ministry halted the administration of flu vaccines on Sunday after three people who were inoculated died, a spokeswoman said. A fourth died later, Israeli media reported"
by The Associated Press, Published by: The Herald Tribune -- 10/22/2006

4. "Requirements for Administration of all vaccines"
"Dry natural rubber is used in syringe plungers and vial stoppers. Dry natural rubber and natural rubber latex contain the same impurities (e.g. plant proteins) believed to be responsible for the allergic reactions, but in lesser amounts than latex. Allergic reactions (including anaphylaxis) after vaccination procedures are rare."
Online, Massachusetts Dep’t of Public Health (Mass. Imuniz. Program) -- 10/21/2006

5. "The vial stopper contains dry natural rubber that may cause hypersensitivity reactions when handled by, or when the product is administered to, persons with known or possible latex sensitivity."
"The vial stopper contains dry natural rubber that may cause hypersensitivity reactions when handled by, or when the product is administered to, persons with known or possible latex sensitivity."
Dryvax® Package Insert (Wyeth Laboratories, Inc.), FDA -- 10/21/2006

6. "Latex allergy: diagnosis and management"
"Latex allergy is an IgE-mediated immediate hypersensitivity response to natural rubber latex (NRL) protein with a variety of clinical signs ranging from contact urticaria, angioedema, asthma, and anaphylaxis."
James S. Taylor et al, Dermatologic Therapy Volume 17 Page 289 -- 9/1/2004

7. "Smallpox Vaccine: Contraindications, Administration, and Adverse Reactions"
"Latex allergy. Patients who are allergic to latex should not be vaccinated. Note that the vaccine vial stopper contains rubber."
Maurer, Douglas M., et al, American Family Physician -- 9/1/2003

8. "Occupational allergies caused by latex."
"Allergy to natural rubber latex is an important cause of occupational allergy in healthcare workers."
Ahmed DD, et al, Immunol Allergy Clin North Am. 2003 May; 23(2):205-19. -- 5/1/2003

9. "Ophthalmological and Biological Features of the Oculorespiratory Syndrome after Influenza Vaccination"
"We report the ophthalmological and laboratory findings of 6 patients who, after influenza vaccination, were affected by oculorespiratory syndrome (ORS), complaining of red eyes, photophobia, blurred vision, palpebral edema, ocular pain and itching, and conjunctival secretions."
Marie Josée Fredette, et al, Clinical Infectious Diseases ;37:1136-1138 -- 1/1/2003

10. "Latex allergy: a health care problem of epidemic proportions."
" The induction of latex allergy commonly occurs after exposure of skin or mucous membrane to natural rubber latex. It is usually a type I, immediate hypersensitivity reaction mediated by IgE which can range from mild skin erythema to anaphylaxis and death."
Agarwal S, et al, Eur J Dermatol. 2002 Jul-Aug;12(4):311-5. -- 7/1/2002

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