A mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?sid=602977


Chemical Descriptions:
United States National Library of Medicine: PubChem
http://pubchem.ncbi.nlm.nih.gov/summary/summary.cgi?cid=5702105

Adverse effects
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=%22Polymyxin%20B%2fadverse%20effects%22[Mesh%20Terms%3anoexp

Toxicity
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=%22Polymyxin%20B%2ftoxicity%22[Mesh%20Terms%3anoexp

Poisoning
http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?CMD=search&DB=pubmed&term=%22Polymyxin%20B%2fpoisoning%22[Mesh%20Terms%3anoexp

a.k.a:
polymyxcin B sulfate, PMB


Present in these vaccines:
smallpox (Acambis, Inc.) - new, not licensed
smallpox (Aventis Pasteur)  - not licensed due to expiration
NYVAC – small pox/ new, not licensed
IPOL – 3 types of polio
Fluvirin – influenza virus
Dryvax – smallpox, not licensed d/t expiration
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